Science you can measure

Independently Studied. WHO‑Guided.

Since day one, SOS has invited independent, university‑led research and built its formula around the proven sodium‑glucose co‑transport mechanism used in oral rehydration science.

  • Proven approach informed by WHO/UNICEF ORS principles.
  • Independent trials in lab and real training settings.
  • Low sugar, high function formulation.
Try Now SOS Blogs

*Formulation informed by WHO/UNICEF ORS principles; no affiliation or endorsement implied.*

Vegan Low Sugar Gluten‑Free Independently Studied
SOS hydration — independent research and WHO‑guided formulation
SOS hydration — independent research and WHO‑guided formulation
Effectiveness of SOS for highly trained middle-distance runners 

Effectiveness of SOS for highly trained middle-distance runners 

Independent, peer-reviewed study into effectiveness of SOS for highly trained middle-distance runners following a high intensity interval training session.

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effectiveness of excess sugar in sports drinks

effectiveness of excess sugar in sports drinks

Independent study into the effectiveness of excess sugar in sports drinks - High Performance Sport Laboratory at Auckland University of Technology 2015.

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osmolarity testing

osmolarity testing

Research conducted by a verified third party specialist osmolarity testing lab.

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Covid hydration management using SOS.

Covid hydration management using SOS.

White paper in association with the American bio defense institute on military and Covid hydration management using SOS.

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Third-Party Empirical Research

Evidence & ORS Science

SOS is informed by the World Health Organization (WHO) / UNICEF Oral Rehydration Solution (ORS) principles and falls within the typical ORS ranges, supported by over 50 years of dehydration research. The studies below explore the effectiveness of ORS and, where relevant, our specific formulation.

Do small differences in hydration status affect mood and mental performance?

Do small differences in hydration status affect mood and mental performance?

Benton D., Young H.A. · 2004 · Nutrition Reviews 73(Suppl 2): p83–96

Review discussing hydration status and its impact on mood and cognitive performance.

Cognition
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Oral Rehydration Solution: A 'low tech' oft neglected therapy

Oral Rehydration Solution: A 'low tech' oft neglected therapy

Nutrition issues in gastroenterology · 2004 · Series 21: p51–62

Overview of ORS therapy and its clinical effectiveness.

ORS
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Oral rehydration vs IV therapy for pediatric gastroenteritis

Oral rehydration vs IV therapy for pediatric gastroenteritis

Bellemare et al. · 2004 · BMC Medicine 2:11

Meta-analysis comparing oral and IV rehydration efficacy in children.

Clinical
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Intravenous versus Oral rehydration: physiological, performance, and legal considerations

Intravenous versus Oral rehydration: physiological, performance, and legal considerations

Casa D. et al. · 2008 · ACSM Curr Sports Med Rep 7(4):41–49

Comparison of IV and oral rehydration in sports contexts.

Sports Med
Details

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Nutritional Information comparison

SOS Internal · 2016 · Report

Nutritional comparison of SOS vs reference beverages.

Product
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Diuretic-induced dehydration and competitive running performance

Diuretic-induced dehydration and competitive running performance

Armstrong L.E., Costill D.L., Fink W.J. · 1985 · Med Sci Sports Exerc 17:456–461

Influence of dehydration on running performance.

Performance
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Effects of body water loss on physiological function and exercise performance

Effects of body water loss on physiological function and exercise performance

Sawka M.N., Pandolf K.B. · 1990 · Perspectives in Exercise Science & Sports Medicine 3

Foundational text on dehydration and performance.

Physiology
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Impact of mild dehydration on wellness and exercise performance

Maughan · 2003 · Eur J Clin Nutr 57(Suppl 2): S19–23

Review of mild dehydration effects on health and performance.

Performance
Details

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WHO Drug Information

WHO · 2002 · Vol. 16(2)

Context for ORS use and guidance.

ORS
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Hypotonic vs isotonic sports drinks and endurance performance

Hypotonic vs isotonic sports drinks and endurance performance

Bonetti D. et al. · 2010 · Sport Science: 63–70

Comparison of drink tonicity on endurance outcomes.

Endurance
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Recent advances of oral rehydration therapy (ORT)

Suh J.S. et al. · 2010 · Electrolyte Blood Press 8:82–86

Advances in ORT mechanisms and applications.

ORT
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Normative data for sweat sodium concentration & sweating rate in athletes

Baker L. et al. · 2015 · Journal of Sports Sciences

Reference values for sweat sodium and rates in athletes.

Sweat
Details

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Co-transport of water by the Na+/glucose cotransporter

PNAS · 1996 · PNAS 93

Fundamental research on sodium-glucose co-transport; see Fig. 4.

Mechanism
Details

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Mayo Clinic — Dehydration

Mayo Clinic · Clinical guidance

General patient-facing overview of dehydration.

Clinical
Details

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*Informed by WHO/UNICEF ORS principles; no affiliation or endorsement implied. For study limitations and methods, see original sources.*